Patient images from left to right by row: FAVA, CLOVES syndrome (top row); FIL (middle row); CLOVES syndrome, FAVA (bottom row).
 
Patient images from left to right by row: FIL (top row); MCAP/M-CM, CLOVES syndrome (middle row); CLOVES syndrome (bottom row).
 
Patient images from left to right by row: CLOVES syndrome, MCAP/M-CM (top row); MCAP/M-CM (middle row); MCAP/M-CM, FAVA (bottom row).
 

Different conditions, one root cause: PIK3CA mutations

Many conditions share the same common cause—PIK3CA mutations. As a result, these conditions are being classified as PIK3CA-Related Overgrowth Spectrum, or PROS.

Different conditions, one root cause: PIK3CA mutations

Many conditions share the same common cause—PIK3CA mutations. As a result, these conditions are being classified as PIK3CA-Related Overgrowth Spectrum, or PROS.

 
Patient images from left to right by row: MCAP/M-CM, CLOVES syndrome, CLOVES syndrome (top row); MCAP/M-CM, MCAP/M-CM, FAVA, CLOVES syndrome (bottom row).
 
Patient images from left to right by row: CLOVES syndrome, MCAP/M-CM (top row); FAVA, FIL, CLOVES syndrome (bottom row).
 
Patient images from left to right by row: FAVA, FIL, FAVA (top row); CLOVES syndrome, CLOVES syndrome (bottom row).
 

Different conditions, one root cause: PIK3CA mutations

Many conditions share the same common cause—PIK3CA mutations. As a result, these conditions are being classified as PIK3CA-Related Overgrowth Spectrum, or PROS.

Explore the cause of PROS conditions

Watch this interactive video to learn more about PIK3CA mutations in PROS.

Hear from families affected by PROS

Five people share what they want others to know about living with PROS.