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Images of various adult and pediatric patients with FAVA, FIL, CLOVES syndrome, and MCAP/M-CM
PROS Mutation icon

Explore the cause of PROS conditions

Watch this interactive video to learn more about PIK3CA mutations in PROS.

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Hear from families affected by PROS

Five people share what they want others to know about living with PROS.

  • KTS (Klippel-Trenaunay Syndrome)

  • CLOVES syndrome (Congenital Lipomatous Overgrowth, Vascular malformations, Epidermal nevi, Scoliosis/skeletal and spinal)

  • ILM (Isolated Lymphatic Malformation)

  • MCAP or M-CM (Megalencephaly-Capillary Malformation)

  • HME (HemiMegalEncephaly)/DMEG (Dysplastic MEGalencephaly)/Focal cortical dysplasia type II

  • HHML (HemiHyperplasia-Multiple Lipomatosis)

  • FIL (Facial Infiltrating Lipomatosis)

  • FAVA (FibroAdipose Vascular Anomaly)

  • Macrodactyly

  • Muscular HH (HemiHyperplasia)

  • FAO (FibroAdipose hyperplasia or Overgrowth)

  • CLAPO syndrome (Capillary malformation of the lower lip, Lymphatic malformation of the face and neck, Asymmetry of the face and limbs, and Partial or generalized Overgrowth)

  • Epidermal nevus, benign lichenoid keratosis, or seborrheic keratosis

  • Other conditions may be identified and characterized as PROS. Talk to your doctor to find out if your condition is a PROS condition

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